![](/__local/F/90/C5/A0958CDA7B1BC247E2E2D5D1659_EC419964_18926.jpg)
研究领域(方向)
1.天然药物化学成分及活性成分研究;
2.天然药物分离分析研究。
个人及工作简历
教育经历
2002/9 - 2008/7,中科院兰州化学物理研究所,分析化学,硕士/博士
1995/9 - 1999/7,武汉大学,应用化学,学士
工作经历
2008/9 -至今,西安交通大学,药学院,副教授
2017/1-2017/12,美国德州理工大学,访问学者
1999/7 - 2008/8,中科院兰州化学物理研究所,中科院西北特色植物资源化学重点实验室,助理研究员
科研项目
1.陕西省自然科学基础研究计划项目,金粟兰属太白七药中抗HBV小分子抑制剂的发现(No.2024JC-YBMS-651),2024.01-2025.12,主持。
2.陕西省技术创新引导专项项目,商洛特色中药材绿色生态防控技术体系创建与示范(No. 2023QYPY2-04)2023.08-2026.07,主持,在研。
3.陕西省自然科学基础研究计划项目,白毛七中倍半萜类抗肿瘤活性成分及作用机制研究(No. 2019JM-203),2019.01-2020.12,主持。
4.西安交通大学基本科研业务费学科综合交叉项目,四叶七中倍半萜类抗肿瘤活性成分及作用机制研究(No. Xjj2016087),2017.01-2019.12,主持。
5.中国博士后科学基金面上资助一等资助.冰盘七和螃蟹七中甾体皂苷类抗肿瘤活性成分的研究(No. 2013M540763),2013.09-2015.06,主持。
6.西安交通大学“必康制药科研基金”,葫芦七中倍半萜类活性成分的研究,2017.01-2018.12,主持。
7.西安交通大学基本科研业务费学科综合交叉项目,四叶七中倍半萜类抗肿瘤活性成分及作用机制研究(No. Xjj2016087),2017.01-2019.12,主持。
8.陕西省自然科学基础研究计划项目,白毛七中倍半萜类抗肿瘤活性成分及作用机制研究(No. 2019JM-203),2019.01-2020.12,主持。
9.国家重点研发计划项目:特色中药材采收加工技术体系构建与高值化综合利用(2019YFC1712606),2023.12-2026.12,参与第二参与者。
10.国家自然科学基金:高密度有序固定FGFR4的细胞膜药物筛选材料的构建及其小分子抑制剂筛选研究,2024.01-2027.12,第二参与者。
学术及科研成果、专利、论文
(一)论文
1.Xiaoyu Xie, Jing Li, Xueyan Zhen, Liang Chen, Wanqing Yuan, Quan Feng,Xia Liu*. Rational construction of fluorescent molecular imprinted polymers for highly efficient glycoprotein detection.Analytica Chimica Acta, 2022, 1209: 339875.
2.Jing Li, Yi-Xuan Yang, Ai-Hong Zhu, Lu-Jun Li,Xia Liu*, Xiaoyu Xie*.Improved detection and recognition of glycoproteins using fluorescent polymers with a molecular imprint based on glycopeptides.Microchimica Acta, 2021, 188: 439.
3.Xiao-Yu Xie, Yi-Xuan Yang, Xin Gao, Qian Liu, Zi-Han Liu, Xiao-Feng Niu,Xia Liu*. Two new dinor-eudesmane sesquiterpenoids from the roots of Chloranthus multistachys.Journal of Asian Natural Product Research, 2022, 24(8), 731-737.
4.Xia Liu, Yi-Xuan Yang, Xin Gao, Qian Liu, Xiao-Na Zhang, Xiao-Feng Niu, Hui Zhang*. A new sesquiterpene from the roots ofChloranthus multistachys.Chemistry of Natural Compounds, 2021, 57(6), 1035-1037.
5.Xia Liu,Jing Li, Jun Li, Qian Liu, Meng Xun. A new flavonoid glycoside fromLigularia fischeri. Chemistry of Natural Compounds, 2019, 55(4), 638-641.
6.Xia Liu, Jun Li, Jun Luo, Dandan Li, Hui Zhang, Zengjun Guo*. A new sesquiterpene from Ligularia fischeri.Chemistry of Natural Compounds, 2016, 52(4), 642-646.
7.Xiao-Feng Niu, Hong-Bo Xu,Xia Liu*, Ting Fan, Lin Qi. Isoquinoline alkaloids fromCorydalis impatiens.Chemistry of Natural Compounds, 2013, 49(1), 187-189.
8.Xiao-Feng Niu, Yong-Mei Li, Hua Hu,Xia Liu*, Lin Qi.Chemical constituents fromCaragana tangutica.Biochemical Systematics and Ecology, 2013, 51, 288-290.
9.Xia Liu, Hui Zhang, Xiao-Feng Niu, Wei Xin, Lin Qi.Steroidal saponins fromSmilacina japonica.Fitoterapia, 2012, 83(4), 812-816.
10.Xiao-Feng Niu,Xia Liu*, Lan Pan, Lin Qi.Oleanene triterpenes fromSedum lineareThunb.Fitoterapia, 2011, 82(7), 960-963.
11.Xia Liu, Yong Liu, Juan Chen, Yan-Ping Shi. Simultaneous analysis of xanthone glycosides inHalenia ellipticaby HPLC-DAD-ESI/MS.Journal of Chromatographic Science, 2010, 48(1), 76-80.
12.Xia Liu, Yuan-Peng Jin,Yan-Ping Shi.Bothriodumin, a shikonin derivative fromBothriospermum secundumMaxim.Pharmazie, 2009, 64(9), 619-621.
13.Xia Liu, Ai-Mei Yang, Yan-Ping Shi*.Determination of flavonoids in Tibetan herbal medicine ofPyrethrum tatsienenseby HPLC with photodiode array detection.Journal of Analytical Chemistry, 2008, 63(5), 472-476.
14.Xia Liu, Quan-Xiang Wu, Xiao-Ning Wei, Yan-Ping Shi*.Novel sesquiterpenes fromLigularia virgaureaspp.Oligocephala.Helvetica Chimica Acta, 2007, 90(9), 1802-1810.
15.Xia Liu, Yan-Ping Shi*. Two new epimeric eremophilane sesquiterpenes from the flower ofCacalia tangutica.Chinese Chemical Letters, 2005, 16(6), 774-776.
16.Xia Liu, Quan-Xiang Wu, Yan-Ping Shi*. Terpenoids from the flower ofCacalia tangutica.Journal of the Chinese Chemical Society, 2005, 52, 369-374.
17.Xia Liu, Yong Liu,Yan-Ping Shi*.Xanthone glycosides from Tibetan herbHalenia elliptica.China Journal of Chinese Materia Medica,2009, 34(5), 580-582.
18.Xiao-yu Xie,Xia Liu, Xiao-yan Pan, Liang Chen, Si-cen Wang*. Surface-imprinted magnetic particles for highly selective sulfonamides recognition prepared by reversible addition fragmentation chain transfer polymerization.Analytical and Bioanalytical Chemistry, 2016, 408(3), 963-970.
19.Xiao-Feng Niu,Xia Liu*, Lan Pan, Lin Qi.Study on steroids ofSedum lineareThunb.China Journal of Chinese Materia Medica,2011, 36(10), 1319-1321.
20.Xia Liu, Lin Qi, Yan Li, Xiao-Feng Niu.Purification of effective components fromSmilacina japonicaby macroporous adsorption resin.Northwest Pharmaceutical Journal,2012, 27(6), 516-519.
21.Xia Liu, Yan-Lin Liu, Xiao-Feng Niu, Lin Qi.Studies on the chemical constituents ofChloranthus multistachys.Journal of Chinese Medicinal Materials,2012, 35(8), 1254-1256.
22.Lin Qi,Xia Liu*, Yu-Fan Liu, Hai Jiang. Study on the pharmacognosy ofTiarella polyphyllaD. Don.Northwest Pharmaceutical Journal,2013, 28(5), 480-482.
(二)科研奖励
1.刘霞(3/9);秦巴山区中药抗炎活性的筛选及作用机理与应用研究,陕西省教育厅,陕西高等学校科学技术奖,一等奖, 2019(牛晓峰;李维凤;刘霞;岐琳;范婷;穆庆丽;姚欢;邢伟;汪秀梅).
2.刘霞(3/5);西部特色中藏药化学成分和质量控制方法学研究,甘肃省科技厅,甘肃省自然科学奖,二等奖, 2006(师彦平;陈娟;刘霞;姜廷福;岳美娥).
(三)授权专利
1.郭增军,李丹丹,张杰,张卉,刘霞,李梦怡,席可.一种酰胺类生物碱的全合成方法, 2015-6-10,中国, CN201410770444.3
2.张卉;郭增军;刘霞;张新新;詹冠群;算盘七中Blestriarene B的提取方法及其抗肿瘤应用, 2021-12-23,中国, CN202111595409.9
3.解笑瑜,刘霞,李静,杨怡璇.基于糖肽的荧光分子印迹聚合物及制备方法和在糖蛋白筛选和检测中的应用. 2021-7-30, CN202110437239.5
4.解笑瑜,王嗣岑,胡琪,魏芬,侯晓芳,刘霞.一种高靶向性细胞膜磁性石墨烯药物筛选材料及制备方法和应用, 2020-7-2,中国, CN202010628688.3
联系方式
E-mail: liuxia1977@mail.xjtu.edu.cn
单位:西安交通大学药学院
地址:西安市雁塔西路76号
邮编:710061